Anti-CASP1 Polyclonal Antibody Knockout Validated
Rabbit Anti-Human CASP1 (Asn120~Asp297) Polyclonal Antibody for WB
COA
Specifications
Antibody Isotype
IgG
Species Reactivity
Human, Pig
Immunogen
Recombinant fragment corresponding to human CASP1 (Asn120~Asp297)
Conjugate
Unconjugated
Applications
Application Notes
Recommended dilution:
WB: 0.5-2 ug/ml
Images
Knockout Varification: Lane 1: Wild-type Raji cell lysate. Lane 2: CASP1 knockout Raji cell lysate.
Predicted MW: 10, 30, 35, 43, 45kDa, Observed MW: 42kDa
Figure. Western Blot.
Sample. Lane1: Porcine Spleen Tissue ; Lane2: Porcine Lung Tissue; Lane3: Human Hela Cells; Lane4: Human Raji Cells.
Target
Alternative Names
ICE; IL1BC; IL1-BC; P45; Interleukin 1 Beta Converting Enzyme; Apoptosis-Related Cysteine Peptidase; Interleukin-1 beta convertase
Entrez Gene ID
UniProt ID
Product Background
Pathway
Amyotrophic lateral sclerosis (ALS); Apoptosis; Caspase cascade in apoptosis; Cellular roles of Anthrax toxin; Cytokine Signaling in Immune system; Cytosolic DNA-sensing pathway; Direct p53 effectors; IFN-gamma pathway;
Custom Antibody Labeling
We offer labeled antibodies using our catalogue antibody products and a broad range of intensely fluorescent dyes and labels including HRP, biotin, ALP, Alexa Fluor® dyes, DyLight® Fluor dyes, R-phycoerythrin (R-PE), at scales from less than 100 μg up to 1 g of IgG antibody. Learn More
Citations
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| Product Name | Cat. No. | Applications | Host Species | Datasheet | Price | Add to Basket |
|---|
Lee, BS; Kang, SU; et al. An agonistic antibody to human death receptor 4 induces apoptotic cell death in head and neck cancer cells through mitochondrial ROS generation. CANCER LETTERS 322:45-57(2012).
Ma, JJ; Yang, BY; et al. Tuberculosis antigen-induced expression of IFN-alpha in tuberculosis patients inhibits production of IL-1 beta. FASEB JOURNAL 28:3238-3248(2014).
Online Inquiry
Catalog # CABT-L2043
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