Anti-CASP7 polyclonal antibody

Antibody Isotype

IgG

Species Reactivity

Human

Immunogen

a 16 amino acid peptide from near the carboxy-terminus of human Caspase-7.

Conjugate

Unconjugated

Alternative Names

CASP7; caspase 7, apoptosis-related cysteine peptidase; MCH3; CMH-1; LICE2; CASP-7; ICE-LAP3; caspase-7; apoptotic protease MCH-3; ICE-like apoptotic protease 3; caspase 7, apoptosis-related cysteine protease

Entrez Gene ID

840

UniProt ID

P55210

Antigen Description

This gene encodes a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce two subunits, large and small, that dimerize to form the active enzyme. The precursor of the encoded protein is cleaved by caspase 3 and 10, is activated upon cell death stimuli and induces apoptosis. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, May 2012]

Pathway

Activation of caspases through apoptosome-mediated cleavage; Alzheimer's disease; Alzheimers Disease; Apoptosis; Apoptosis Modulation and Signaling; Apoptosis Modulation by HSP70; Apoptotic cleavage of cellular proteins; Apoptotic execution phase

We offer labeled antibodies using our catalogue antibody products and a broad range of intensely fluorescent dyes and labels including HRP, biotin, ALP, Alexa Fluor® dyes, DyLight® Fluor dyes, R-phycoerythrin (R-PE), at scales from less than 100 μg up to 1 g of IgG antibody. Learn More