Anti-CH25H polyclonal antibody
Rabbit anti-Human CH25H (aa 190-239) polyclonal antibody for WB
COA
Specifications
Antibody Isotype
IgG
Species Reactivity
Human
Immunogen
Synthetic peptide corresponding to a region within C terminal amino acids 190-239 (VTLLGCHPLT TLTFHVVNIW LSVEDHSGYN FPWSTHRLVP FGWYGGVVHH) of Human CH25H (NP_003947).
Conjugate
Unconjugated
Applications
Application Notes
WB: 1 μg/ml.
Target
Alternative Names
CH25H; cholesterol 25-hydroxylase; h25OH; cholesterol 25-monooxygenase; C25H;
Entrez Gene ID
UniProt ID
Product Background
Antigen Description
CH25H is involved in cholesterol and lipid metabolism and catalyses the formation of 25-hydroxycholesterol from cholesterol, leading to repression of cholesterol biosynthetic enzymes. It may play an important role in regulating lipid metabolism by synthesizing a corepressor that blocks sterol regulatory element binding protein (SREBP) processing.
Pathway
Bile acid and bile salt metabolism; Metabolism; Metabolism of lipids and lipoproteins; Primary bile acid biosynthesis; Synthesis of bile acids and bile salts;
Custom Antibody Labeling
We offer labeled antibodies using our catalogue antibody products and a broad range of intensely fluorescent dyes and labels including HRP, biotin, ALP, Alexa Fluor® dyes, DyLight® Fluor dyes, R-phycoerythrin (R-PE), at scales from less than 100 μg up to 1 g of IgG antibody. Learn More
Citations
Have you cited DPABH-25497 in a publication? Let us know and earn a reward for your research.
| Product Name | Cat. No. | Applications | Host Species | Datasheet | Price | Add to Basket |
|---|
Ichikawa, T; Sugiura, H; et al. 25-Hydroxycholesterol promotes fibroblast-mediated tissue remodeling through NF-kappa B dependent pathway. EXPERIMENTAL CELL RESEARCH 319:1176-1186(2013).
Online Inquiry
Catalog # DPABH-25497
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