Specifications
Immunogen
Fibrin degradation products.
Target
Alternative Names
FGA; fibrinogen alpha chain; fibrinogen, A alpha polypeptide; Fib2; MGC119422; MGC119423; MGC119425;
Product Background
Antigen Description
Fibrinogen has a double function: yielding monomers that polymerize into fibrin and acting as a cofactor in platelet aggregation.
Pathway
Amyloids, organism-specific biosystem; Blood Clotting Cascade, organism-specific biosystem; Common Pathway, organism-specific biosystem; Complement and coagulation cascades, organism-specific biosystem; Complement and coagulation cascades, conserved biosystem; Disease, organism-specific biosystem; Formation of Fibrin Clot (Clotting Cascade), organism-specific biosystem;
Citations
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Kolarz, B; Majdan, M; et al. Antibodies against cyclic citrullinated peptide don't decrease after 6 months of infliximab treatment in refractory rheumatoid arthritis. RHEUMATOLOGY INTERNATIONAL 31:1439-1443(2011).
Mobarrez, F; He, S; et al. Atorvastatin reduces thrombin generation and expression of tissue factor, P-selectin and GPIIIa on platelet-derived microparticles in patients with peripheral arterial occlusive disease. THROMBOSIS AND HAEMOSTASIS 106:344-352(2011).