Anti-KLF4 polyclonal antibody

Antibody Isotype

IgG

Species Reactivity

Mouse

Immunogen

Synthetic peptide corresponding to Mouse KLF4 aa 1-100 conjugated to Keyhole Limpet Haemocyanin (KLH).Database link: Q60793

Conjugate

Unconjugated

Application Notes

ICC/IF: 1 μg/ml; WB: 1 μg/ml; IHC-P: 1 μg/ml.

Alternative Names

KLF4; Kruppel-like factor 4 (gut); Krueppel-like factor 4; gut-enriched krueppel-like factor; epithelial zinc finger protein EZF; Kruppel-like factor 4 (Gut enriched kruppel-like factor) (Epithelial zinc-finger protein EZF); EZF; Zie; Gklf;

Entrez Gene ID

16600

UniProt ID

F2YID5

Antigen Description

Transcription factor; can act both as activator and as repressor. Binds the 5-CACCC-3 core sequence. Binds to the promoter region of its own gene and can activate its own transcription. Regulates the expression of key transcription factors during embryonic development. Plays an important role in maintaining embryonic stem cells, and in preventing their differentiation. Required for establishing the barrier function of the skin and for postnatal maturation and maintenance of the ocular surface. Involved in the differentiation of epithelial cells and may also function in skeletal and kidney development. Contributes to the down-regulation of p53/TP53 transcription.

Pathway

Developmental Biology; PluriNetWork; Transcriptional Regulation of White Adipocyte Differentiation;

We offer labeled antibodies using our catalogue antibody products and a broad range of intensely fluorescent dyes and labels including HRP, biotin, ALP, Alexa Fluor® dyes, DyLight® Fluor dyes, R-phycoerythrin (R-PE), at scales from less than 100 μg up to 1 g of IgG antibody. Learn More