Anti-POU5F1 monoclonal antibody

Antibody Isotype

IgG

Clone

5I3

Species Reactivity

Human

Immunogen

Recombinant full length protein corresponding to Human Oct4.

Conjugate

Unconjugated

Application Notes

WB: 1/500 - 1/1000; ELISA: 1/5000; IHC-P: 1/50 - 1/100;

Alternative Names

POU5F1; POU class 5 homeobox 1; OTF3, POU domain class 5, transcription factor 1; POU domain, class 5, transcription factor 1; MGC22487; OCT3; Oct4; octamer-binding protein 3; octamer-binding protein 4; POU domain transcription factor OCT4; octamer-bindi

Entrez Gene ID

5460

UniProt ID

M1S623

Antigen Description

Transcription factor that binds to the octamer motif (5-ATTTGCAT-3). Forms a trimeric complex with SOX2 on DNA and controls the expression of a number of genes involved in embryonic development such as YES1, FGF4, UTF1 and ZFP206. Critical for early embryogenesis and for embryonic stem cell pluripotency.

Pathway

HIF-2-alpha transcription factor network, organism-specific biosystem; Wnt Signaling Pathway and Pluripotency, organism-specific biosystem;

We offer labeled antibodies using our catalogue antibody products and a broad range of intensely fluorescent dyes and labels including HRP, biotin, ALP, Alexa Fluor® dyes, DyLight® Fluor dyes, R-phycoerythrin (R-PE), at scales from less than 100 μg up to 1 g of IgG antibody. Learn More