Anti-POU5F1 monoclonal antibody
Mouse anti-Human POU5F1 monoclonal antibody for ICC/IF, FC, IP, WB, IHC-P
Specifications
Antibody Isotype
IgG2b
Clone
HU597
Species Reactivity
Mouse, Human
Immunogen
Recombinant fragment within Human Oct4 aa 1-182. The exact sequence is proprietary.Database link: Q01860
Conjugate
Unconjugated
Applications
Application Notes
ICC/IF: 1/100 - 1/1000; Flow Cyt: 1/50; IP: 1/100 - 1/500; WB: 1/500 - 1/3000; IHC-P: 1/100 - 1/1000.
Target
Alternative Names
POU5F1; POU class 5 homeobox 1; OTF3, POU domain class 5, transcription factor 1; POU domain, class 5, transcription factor 1; MGC22487; OCT3; Oct4; octamer-binding protein 3; octamer-binding protein 4; POU domain transcription factor OCT4; octamer-bindi
Entrez Gene ID
UniProt ID
Product Background
Antigen Description
Transcription factor that binds to the octamer motif (5-ATTTGCAT-3). Forms a trimeric complex with SOX2 on DNA and controls the expression of a number of genes involved in embryonic development such as YES1, FGF4, UTF1 and ZFP206. Critical for early embryogenesis and for embryonic stem cell pluripotency.
Pathway
HIF-2-alpha transcription factor network, organism-specific biosystem; Wnt Signaling Pathway and Pluripotency, organism-specific biosystem;
Custom Antibody Labeling
We offer labeled antibodies using our catalogue antibody products and a broad range of intensely fluorescent dyes and labels including HRP, biotin, ALP, Alexa Fluor® dyes, DyLight® Fluor dyes, R-phycoerythrin (R-PE), at scales from less than 100 μg up to 1 g of IgG antibody. Learn More
Citations
Have you cited DCABH-7898 in a publication? Let us know and earn a reward for your research.
| Product Name | Cat. No. | Applications | Host Species | Datasheet | Price | Add to Basket |
|---|---|---|---|---|---|---|
| Mouse IgG2b Isotype Control | DAGIC1236 | FC EIA WB | Mouse |
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Goel, S; Fujihara, M; et al. Multipotential ability of primitive germ cells from neonatal pig testis cultured in vitro. REPRODUCTION FERTILITY AND DEVELOPMENT 21:696-708(2009).
Markoullis, K; Bulian, D; et al. Mycoplasma contamination of murine embryonic stem cells affects cell parameters, germline transmission and chimeric progeny. TRANSGENIC RESEARCH 18:71-87(2009).
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Catalog # DCABH-7898
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