Anti-POU5F1 monoclonal antibody
Mouse anti-Human POU5F1 monoclonal antibody for sELISA, WB, ELISA
COA
Specifications
Antibody Isotype
IgG2b
Species Reactivity
Human
Immunogen
Recombinant fragment corresponding to Human Oct4 aa 81-164.Sequence: WFCNRRQKGKRSSSDYAQREDFEAAGSPFSGGPVSFPLAPGPHFGTPGYG SPHFTALYSSVPFPEGEAFPPVSVTTLGSPMHSN
Conjugate
Unconjugated
Applications
Application Notes
Sandwich ELISA: 5 μg/ml; WB: 1 - 5 μg/ml.
Target
Alternative Names
POU5F1; POU class 5 homeobox 1; OTF3, POU domain class 5, transcription factor 1; POU domain, class 5, transcription factor 1; MGC22487; OCT3; Oct4; octamer-binding protein 3; octamer-binding protein 4; POU domain transcription factor OCT4; octamer-bindi
Entrez Gene ID
UniProt ID
Product Background
Antigen Description
Transcription factor that binds to the octamer motif (5-ATTTGCAT-3). Forms a trimeric complex with SOX2 on DNA and controls the expression of a number of genes involved in embryonic development such as YES1, FGF4, UTF1 and ZFP206. Critical for early embryogenesis and for embryonic stem cell pluripotency.
Pathway
HIF-2-alpha transcription factor network, organism-specific biosystem; Wnt Signaling Pathway and Pluripotency, organism-specific biosystem;
Custom Antibody Labeling
We offer labeled antibodies using our catalogue antibody products and a broad range of intensely fluorescent dyes and labels including HRP, biotin, ALP, Alexa Fluor® dyes, DyLight® Fluor dyes, R-phycoerythrin (R-PE), at scales from less than 100 μg up to 1 g of IgG antibody. Learn More
Citations
Have you cited DCABH-9788 in a publication? Let us know and earn a reward for your research.
| Product Name | Cat. No. | Applications | Host Species | Datasheet | Price | Add to Basket |
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Ledda, S; Bogliolo, L; et al. Characterization, isolation and culture of primordial germ cells in domestic animals: recent progress and insights from the ovine species. THERIOGENOLOGY 74:534-543(2010).
Jones, TD; Ulbright, TM; et al. OCT4 staining in testicular tumors - A sensitive and specific marker for seminoma and embryonal carcinoma. AMERICAN JOURNAL OF SURGICAL PATHOLOGY 28:935-940(2004).
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Catalog # DCABH-9788
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