Magic™ Anti-POU5F1 polyclonal antibody
Chicken anti-Human POU5F1 (aa 1-100) polyclonal antibody for WB, ICC/IF
COA
Specifications
Antibody Isotype
IgY
Species Reactivity
Mouse
Immunogen
Synthetic peptide within Human Oct4 aa 1-100 conjugated to Keyhole Limpet Haemocyanin (KLH). The exact sequence is proprietary.
Conjugate
Unconjugated
Applications
Application Notes
WB: 1 μg/ml; ICC/IF: 5 μg/ml.
Target
Alternative Names
POU5F1; POU class 5 homeobox 1; OCT3; OCT4; OTF3; OTF4; OTF-3; Oct-3; Oct-4; POU domain, class 5, transcription factor 1; octamer-binding protein 3; octamer-binding protein 4; POU domain transcription factor OCT4; octamer-binding transcription factor 3; P
Entrez Gene ID
UniProt ID
Product Background
Antigen Description
Transcription factor that binds to the octamer motif (5-ATTTGCAT-3). Forms a trimeric complex with SOX2 on DNA and controls the expression of a number of genes involved in embryonic development such as YES1, FGF4, UTF1 and ZFP206. Critical for early embryogenesis and for embryonic stem cell pluripotency.
Pathway
Cardiac Progenitor Differentiation; HIF-2-alpha transcription factor network; POU5F1 (OCT4), SOX2, NANOG repress genes related to differentiation; Transcriptional regulation of pluripotent stem cells
Custom Antibody Labeling
We offer labeled antibodies using our catalogue antibody products and a broad range of intensely fluorescent dyes and labels including HRP, biotin, ALP, Alexa Fluor® dyes, DyLight® Fluor dyes, R-phycoerythrin (R-PE), at scales from less than 100 μg up to 1 g of IgG antibody. Learn More
Citations
Have you cited DPABH-25558 in a publication? Let us know and earn a reward for your research.
| Product Name | Cat. No. | Applications | Host Species | Datasheet | Price | Add to Basket |
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Sonne, SB; Perrett, RM; et al. Analysis of SOX2 expression in developing human testis and germ cell neoplasia. INTERNATIONAL JOURNAL OF DEVELOPMENTAL BIOLOGY 54:755-760(2010).
Bode, PK; Barghorn, A; et al. MAGEC2 is a sensitive and novel marker for seminoma: a tissue microarray analysis of 325 testicular germ cell tumors. MODERN PATHOLOGY 24:829-835(2011).
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Catalog # DPABH-25558
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