Anti-POU5F1 polyclonal antibody

Antibody Isotype

IgG

Species Reactivity

Mouse, Rat, Human, Pig, Macaque Monkey

Immunogen

Synthetic peptide within Human Oct4 aa 1-14 (N terminal). The exact sequence is proprietary.Sequence: MAGHLASDFAFSPC Database link: P20263

Conjugate

Unconjugated

Application Notes

IHC-Fr: 20μg/ml; WB: 1 - 2μg/ml; IP: 20μg/ml; Flow Cyt: IHC-P: 1/100;

Alternative Names

POU5F1; POU class 5 homeobox 1; OCT3; OCT4; OTF3; OTF4; OTF-3; Oct-3; Oct-4; POU domain, class 5, transcription factor 1; octamer-binding protein 3; octamer-binding protein 4; POU domain transcription factor OCT4; octamer-binding transcription factor 3; P

Entrez Gene ID

5460

UniProt ID

M1S623

Antigen Description

Transcription factor that binds to the octamer motif (5-ATTTGCAT-3). Forms a trimeric complex with SOX2 on DNA and controls the expression of a number of genes involved in embryonic development such as YES1, FGF4, UTF1 and ZFP206. Critical for early embryogenesis and for embryonic stem cell pluripotency.

Pathway

Cardiac Progenitor Differentiation; HIF-2-alpha transcription factor network; POU5F1 (OCT4), SOX2, NANOG repress genes related to differentiation; Transcriptional regulation of pluripotent stem cells

We offer labeled antibodies using our catalogue antibody products and a broad range of intensely fluorescent dyes and labels including HRP, biotin, ALP, Alexa Fluor® dyes, DyLight® Fluor dyes, R-phycoerythrin (R-PE), at scales from less than 100 μg up to 1 g of IgG antibody. Learn More