Specifications
Species Reactivity
Human, Bovine, Cat, Green monkey, Horse
Immunogen
Recombinant human p53.
Applications
Application Notes
Flow Cyt: Neat
Target
Alternative Names
TP53; tumor protein p53; P53; BCC7; LFS1; TRP53; cellular tumor antigen p53; antigen NY-CO-13; tumor protein 53; phosphoprotein p53; p53 tumor suppressor; mutant tumor protein 53; transformation-related protein 53;
Product Background
Pathway
AMPK signaling; Activation of BH3-only proteins; Activation of NOXA and translocation to mitochondria; Activation of PUMA and translocation to mitochondria; Alzheimers Disease; Amyotrophic lateral sclerosis (ALS); Apoptosis; Aurora A signaling;
Citations
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Weisbrod, AB; Zhang, LS; et al. Altered PTEN, ATRX, CHGA, CHGB, and TP53 Expression Are Associated with Aggressive VHL-Associated Pancreatic Neuroendocrine Tumors. HORMONES & CANCER 4:165-175(2013).
Nenutil, R; Smardova, J; et al. Discriminating functional and non-functional p53 in human tumours by p53 and MDM2 immunohistochemistry. JOURNAL OF PATHOLOGY 207:251-259(2005).