Specifications
Species Reactivity
Human, Bovine, Cat, Green monkey, Horse
Immunogen
Recombinant human p53.
Applications
Application Notes
Flow Cyt: Neat
Target
Alternative Names
TP53; tumor protein p53; P53; BCC7; LFS1; TRP53; cellular tumor antigen p53; antigen NY-CO-13; tumor protein 53; phosphoprotein p53; p53 tumor suppressor; mutant tumor protein 53; transformation-related protein 53;
Product Background
Pathway
AMPK signaling; Activation of BH3-only proteins; Activation of NOXA and translocation to mitochondria; Activation of PUMA and translocation to mitochondria; Alzheimers Disease; Amyotrophic lateral sclerosis (ALS); Apoptosis; Aurora A signaling;
Citations
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Seemann, S; Maurici, D; et al. The tumor suppressor gene TP53: Implications for cancer management and therapy. CRITICAL REVIEWS IN CLINICAL LABORATORY SCIENCES 41:551-583(2004).
Morse, HC; Kearney, JF; et al. Cells of the marginal zone - origins, function and neoplasia. LEUKEMIA RESEARCH 25:169-178(2001).