Human BAK1 blocking peptide

Product Overview

Blocking/Immunizing peptide for anti-BAK1 antibody

Target

BAK1

Nature

Synthetic

Tag/Conjugate

Unconjugated

Application Notes

For in vitro research use only. Not intended for any diagnostic or therapeutic purpose. Not for human or animal consumption.

Format

Lyophilized powder

Preservative

None

Storage

Shipped at ambient temperature, store at -20°C.

UniProt ID

578

Antigen Description

The protein encoded by this gene belongs to the BCL2 protein family. BCL2 family members form oligomers or heterodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. This protein localizes to mitochondria, and functions to induce apoptosis. It interacts with and accelerates the opening of the mitochondrial voltage-dependent anion channel, which leads to a loss in membrane potential and the release of cytochrome c. This protein also interacts with the tumor suppressor P53 after exposure to cell stress. [provided by RefSeq, Jul 2008]

Function

BH domain binding; chaperone binding; heat shock protein binding; identical protein binding; metal ion binding; protein binding; protein heterodimerization activity; protein homodimerization activity;

Synonyms

BAK1; BCL2-antagonist/killer 1; BAK; CDN1; BCL2L7; BAK-LIKE; bcl-2 homologous antagonist/killer; bcl2-L-7; BCL2-like 7 protein; bcl-2-like protein 7; apoptosis regulator BAK; pro-apoptotic protein BAK;