Anti-Human EphA2 monoclonal antibody, Functional Grade Functional Grade
Mouse anti-Human EphA2 monoclonal antibody for IHC-P, IP, FuncS
COA
Specifications
Antibody Isotype
IgG2b, κ
Clone
C3E7
Species Reactivity
Human
Immunogen
Human EphA2 isolated from Ras-transformed MCF-10A cells.
Conjugate
Functional Grade
Images
Western blot confirmation of the level of phosphorylated EphA2 following stimulation with EA2 antibody; which recognizes the extracellular domain of EphA2.
Immunohistochemistry
Immunohistochemistry for EphA3 and EphA2 in a mouse brain carrying G48a tumors. The hippocampal area A. and tumor-normal brain margin B. were examined. The hippocampal area did not stain specifically for either the receptor, except for tumor-infiltrating cells (arrows).
Immunohistochemistry for EphA3 and EphA2 in a mouse brain carrying G48a tumors. The hippocampal area A. and tumor-normal brain margin B. were examined. The hippocampal area did not stain specifically for either the receptor, except for tumor-infiltrating cells (arrows).
Target
Alternative Names
EPHA2; Eph receptor A2; Eck; Myk2; Sek2; Sek-2
Entrez Gene ID
UniProt ID
Citations
Publication (3)
Publication (3)
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Lee, JW; Stone, RL; et al. EphA2 Targeted Chemotherapy Using an Antibody Drug Conjugate in Endometrial Carcinoma. CLINICAL CANCER RESEARCH 16:2562-2570(2010).
Hammond, SA; Lutterbuese, R; et al. Selective targeting and potent control of tumor growth using an EphA2/CD3-bispecific single-chain antibody construct. CANCER RESEARCH 67:3927-3935(2007).
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Catalog # CABT-Z469M
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