Anti-Human VEGFR2 (Ramucirumab) monoclonal antibody, Functional Grade Functional Grade
Human anti-Human VEGFR2 (Ramucirumab) monoclonal antibody for FA
COA
Specifications
Antibody Isotype
IgG1
Clone
Ramucirumab
Species Reactivity
Human
Immunogen
Human VEGFR2.
Conjugate
Functional Grade
Images
Flow cytometry.
Flow cytometry analysis of EPC in representative stem cell grafts from NHL and MM patients. Gating on ALDH hi cells in order to define cells with stem or progenitor characteristics. EPC were subsequent defined as triple positive CD34+VEGFR2+CD133+ cells (red arrow).
Immunohistochemistry.
Immunohistochemical staining of VEGFR-2 in gastric cancer tissues. (C) VEGFR-2 (?). (D) VEGFR-2 (+). (E) VEGFR-2 (++ - +++). Magnification, ×200. VEFGR-2, VEGF receptor 2.
Tumor growth inhibition
Effects of Ramucirumab and/or Paclitaxel on cell cycle progression in gastric cancer cell lines. (a) AGS, NCI-N87 human gastric cancer cells were synchronized in the G2/M phase of the cell cycle (T0).
Effects of Ramucirumab and/or Paclitaxel on cell cycle progression in gastric cancer cell lines. (a) AGS, NCI-N87 human gastric cancer cells were synchronized in the G2/M phase of the cell cycle (T0).
Target
Alternative Names
KDR; kinase insert domain receptor (a type III receptor tyrosine kinase); vascular endothelial growth factor receptor 2; CD309; FLK1; VEGFR
Entrez Gene ID
UniProt ID
Citations
Publication (3)
Publication (3)
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Cho, DH; Choi, YJ; et al. Nitric oxide production and regulation of endothelial nitric-oxide synthase phosphorylation by prolonged treatment with troglitazone - Evidence for involvement of peroxisome proliferator-activated receptor (PPAR)gamma-dependent and PPAR gamma-independent signaling pathways. JOURNAL OF BIOLOGICAL CHEMISTRY 279:2499-2506(2004).
Tian, XJ; Meng, L; et al. Coexpression of vascular endothelial growth factor and its receptor KDR on gastric adenocarcinoma MGC803 cell line and stimulation of exogenous VEGF165 to MGC803 cells. SCIENCE IN CHINA SERIES C-LIFE SCIENCES 43:88-95(2000).
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Catalog # CABT-Z696H
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