Anti-CH25H monoclonal antibody

Antibody Isotype

IgG2b

Clone

2H9

Species Reactivity

Human

Immunogen

CH25H (AAH17843, 142 a.a. ~ 247 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

Conjugate

Unconjugated

Alternative Names

cholesterol 25-hydroxylase; Cholesterol 25-monooxygenase; h25OH; EC 1.14.99.38; C25H; OTTHUMP00000020057

Entrez Gene ID

9023

UniProt ID

O95992

Antigen Description

This is an intronless gene that is involved in cholesterol and lipid metabolism. The encoded protein is a membrane protein and contains clusters of histidine residues essential for catalytic activity. Unlike most other sterol hydroxylases, this enzyme is a member of a small family of enzymes that utilize diiron cofactors to catalyze the hydroxylation of hydrophobic substrates.
Mouse monoclonal antibody raised against a partial recombinant CH25H.

Pathway

Bile acid and bile salt metabolism, organism-specific biosystem; Metabolism of lipids and lipoproteins, organism-specific biosystem; Primary bile acid biosynthesis, organism-specific biosystem; Primary bile acid biosynthesis, conserved biosystem; Synthesis of bile acids and bile salts, organism-specific biosystem.

We offer labeled antibodies using our catalogue antibody products and a broad range of intensely fluorescent dyes and labels including HRP, biotin, ALP, Alexa Fluor® dyes, DyLight® Fluor dyes, R-phycoerythrin (R-PE), at scales from less than 100 μg up to 1 g of IgG antibody. Learn More