Anti-PRKD3 monoclonal antibody

Antibody Isotype

IgG2a

Clone

5H8

Species Reactivity

Human

Immunogen

PRKD3 (AAH30706, 1 a.a. ~ 100 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

Conjugate

Unconjugated

Alternative Names

protein kinase D3; PKC-NU; EPK2; PKD3; PRKCN; nPKC-NU; protein kinase C, nu; protein-serine/threonine kinase; Protein kinase C nu type; serine/threonine-protein kinase D3; Protein kinase EPK2; EC 2.7.11.13; EC 2.7.11; OTTHUMP00000126953

Entrez Gene ID

23683

UniProt ID

O94806

Antigen Description

Protein kinase C (PKC) is a family of serine- and threonine-specific protein kinases that can be activated by calcium and the second messenger diacylglycerol. PKC family members phosphorylate a wide variety of protein targets and are known to be involved in diverse cellular signaling pathways. PKC family members also serve as major receptors for phorbol esters, a class of tumor promoters. Each member of the PKC family has a specific expression profile and is believed to play a distinct role. The protein encoded by this gene is one of the PKC family members. This kinase can be activated rapidly by the agonists of G protein-coupled receptors. It resides in both cytoplasm and nucleus, and its nuclear accumulation is found to be dramatically enhanced in response to its activation. This kinase can also be activated after B-cell antigen receptor (BCR) engagement, which requires intact phopholipase C gamma and the involvement of other PKC family members.
Mouse monoclonal antibody raised against a partial recombinant PRKD3.

Pathway

G Protein Signaling Pathways, organism-specific biosystem; IL-4 signaling Pathway, organism-specific biosystem

We offer labeled antibodies using our catalogue antibody products and a broad range of intensely fluorescent dyes and labels including HRP, biotin, ALP, Alexa Fluor® dyes, DyLight® Fluor dyes, R-phycoerythrin (R-PE), at scales from less than 100 μg up to 1 g of IgG antibody. Learn More