Buffer
PBS, 50% Glycerol, 1.45% Sodium chloride, pH7.4
Introduction
Matrix metallopeptidase 9 (MMP-9), also known as 92 kDa type IV collagenase, 92 kDa gelatinase or gelatinase B (GELB), is a matrixin, a class of enzymes that belong to the zinc-metalloproteinases family involved in the degradation of the extracellular matrix. In humans the MMP9 gene. encodes for a signal peptide, a propeptide, a catalytic domain with inserted three repeats of fibronectin type II domain followed by a C-terminal hemopexin-like domain.
Keywords
MMP9; Matrix metallopeptidase 9
Citations
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Kyriakides, TR; Wulsin, D; et al. Mice that lack matrix metalloproteinase-9 display delayed wound healing associated with delayed reepithelization and disordered collagen fibrillogenesis. MATRIX BIOLOGY 28:65-73(2009).
Yamamori, H; Hashimoto, R; et al. Plasma levels of mature brain-derived neurotrophic factor (BDNF) and matrix metalloproteinase-9 (MMP-9) in treatment-resistant schizophrenia treated with clozapine. NEUROSCIENCE LETTERS 556:37-41(2013).