Alternative Names
Neurofilament L; NF-L; Neurofilament low molecular weight protein
Buffer
0.01M pH7.2 PBS, with 20% glycerol
Preservative
0.05% Sodium Azide
Storage
Store at -20°C for long term. Avoid freeze / thaw cycles.
Introduction
NEFL or Neurofilament light polypeptide is a protein that is encoded through the NEFL gene. NEFL is correlated to a disease called Charcot–Marie–Tooth. The protein's light subunit is determined by immunoassays in the plasma and cerebrospinal fluid, if present, it can indicate on axonal damage in neurological diseases. By doing so, NEFL can act as a marker for Huntington's disease, Amyotrophic Lateral Sclerosis and multiple sclerosis.
Antigen Description
Neurofilament L recombinant protein expressed from insect cells
Keywords
NEFL; Neurofilament light polypeptide; NFL; NF-L; Neurofilament protein
Citations
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Bianco, J; Gueye, Y; et al. VITAMIN D-3 IMPROVES RESPIRATORY ADJUSTMENT TO FATIGUE AND H-REFLEX RESPONSES IN PARAPLEGIC ADULT RATS. NEUROSCIENCE 188:182-192(2011).
Mihara, T; Ueda, A; et al. Detection of new anti-neutral glycosphingolipids antibodies and their effects on Trk neurotrophin receptors. FEBS LETTERS 580:4991-4995(2006).