Recombinant H. pylori CagA VacA chimeric protein [His]

Target

H. pylori CagA

Nature

Recombinant

Tag/Conjugate

His

Purity

> 90 % as determined by SDS-PAGE

Format

Liquid

Buffer

25mM Tris-HCl, 0.02%SDS, pH 8.5

Preservative

None

Storage

Store at -20°C to -80°C. Avoid repeated freeze/thaw cycles

Introduction

Helicobacter pylori is a Gram-negative, microaerophilic bacterium that can inhabit various areas of the stomach, particularly the antrum. It causes a chronic low-level inflammation of the stomach lining and is strongly linked to the development of duodenal and gastric ulcers and stomach cancer. Over 80 percent of individuals infected with the bacterium are asymptomatic. The spiral shaped bacterium Helicobacter pylori is strongly associated with inflammation of the stomach and is also implicated in the development of gastric malignancy. H. pylori is known to cause peptic ulcers and chronic gastritis in human. It is associated with duodenal ulcers and may be involved in development of adenocarcimona and low-grade lymphoma of mucosa associated lymphoid tissue in the stomach.

Keywords

H. pylori; CagA; VacA