Recombinant Human ZNT8 [His]
Recombinant Human Zinc transporter 8 from Sf9 Cells[His]
COA
Nature
Recombinant
Tag/Conjugate
His
Molecular Weight
~27kDa
Alternative Names
SLC30A8, ZnT-8, ZNT8
Purity
> 95% determined by SDS-PAGE
Format
Liquid
Buffer
20mM Tris-HCl buffer (pH 8.0) containing 0.2M NaCl.
Preservative
None
Storage
Store it at +4°C for short term. For long term storage, store it at -20°C ~-70°C. Avoid repeated freeze-thaw cycles.
Introduction
Zinc transporter 8 (ZNT8) is a protein that in humans is encoded by the SLC30A8 gene. ZNT8 is a zinc transporter related to insulin secretion in humans. Certain alleles of the SLC30A8 gene may increase the risk for developing type 2 diabetes, but a loss-of-function mutation appears to greatly reduce the risk of diabetes.
Keywords
SLC30A8; zinc transporter 8; ZnT-8; ZNT8
Citations
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Kawasaki, E; et al. ZnT8 and type 1 diabetes. ENDOCRINE JOURNAL 59:531-537(2012).
Petruzelkova, L; Ananieva-Jordanova, R; et al. The dynamic changes of zinc transporter 8 autoantibodies in Czech children from the onset of Type 1 diabetes mellitus. DIABETIC MEDICINE 31:165-171(2014).
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