Recombinant Epstein-Barr Virus p54 Early Antigen [His]

Product Overview

A DNA sequence encoding the Epstein-Barr virus p54 early antigen (a.a 257-404) was expressed with a polyhistidine tag at the N-terminusl.

Target

EBV Early Antigen

Nature

Recombinant

Tag/Conjugate

His

Molecular Weight

20.3 kDa

Alternative Names

p54 early antigen; BMRF1 protein; Epstein-Barr virus p54

Purity

> 95 % as determined by SDS-PAGE

Format

Liquid

Buffer

20 mM phosphate buffer, pH 8.0, with 1 M NaCl and 0.1% polyoxyethelene (10) tridecyl ether and 6 mM urea

Preservative

None

Storage

Store at -20°C to -80°C. Avoid multiple freeze/thaw cycles

Introduction

The Epstein–Barr virus (EBV), also called human herpesvirus5(HHV-4), is a virus of theherpes family, which includes herpes simplex virus 1 and 2, and is one of themost common viruses in humans. It is best known as the cause of infectiousmononucleosis. It is also associated with particular forms of cancer, particularlyHodgkin"s lymphoma, Burkitt"s lymphoma, nasopharyngeal carcinoma, and centralnervous system lymphomas associated with HIV. Finally, there is evidence thatinfection with the virus is associated with a higher risk of certainautoimmune diseases, especially dermatomyositis, systemic lupuserythematosus, rheumatoid arthritis and multiplesclerosis.

Keywords

Epstein–Barr virus; EBV; Early antigen; p54