Specifications
Species Reactivity
Human, Mouse, Rat
Immunogen
A synthetic peptide containing the epitope IS GIC-S*-PL with a phosphorylation site at Serine 1124 of human LRRK2. This sequence is also identical within human, rat and mouse.
Applications
Application Notes
WB: 0.1-1 ug/mL; ELISA: 0.01-0.1 ug/mL; IP: 2-5 ug/mL; IHC: 2-10 ug/mL
Target
Alternative Names
LRRK2; leucine-rich repeat kinase 2; PARK8
Custom Antibody Labeling
We offer labeled antibodies using our catalogue antibody products and a broad range of intensely fluorescent dyes and labels including HRP, biotin, ALP, Alexa Fluor® dyes, DyLight® Fluor dyes, R-phycoerythrin (R-PE), at scales from less than 100 μg up to 1 g of IgG antibody.
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Citations
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Vitte, J; Traver, S; et al. Leucine-Rich Repeat Kinase 2 Is Associated With the Endoplasmic Reticulum in Dopaminergic Neurons and Accumulates in the Core of Lewy Bodies in Parkinson Disease. JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY 69:959-972(2010).
Toyoshima, I; Hasegawa, K; et al. LRRK2 distribution in the human brain revealed by monoclonal antibody. MOVEMENT DISORDERS 23:S12-S12(2008).