Specifications
Species Reactivity
Human, Mouse, Rat, Bovine
Immunogen
A synthetic peptide containing the epitope VNA-pT-EES with a phosphorylation site at Threonine 1491 of human LRRK2. This sequence is also identical within human, rat and mouse
Applications
Application Notes
WB: 0.1-1 ug/mL; ELISA: 0.01-0.1 ug/mL; IP: 2-5 ug/mL; IHC: 2-10 ug/mL
Target
Alternative Names
LRRK2; leucine-rich repeat kinase 2; PARK8
Custom Antibody Labeling
We offer labeled antibodies using our catalogue antibody products and a broad range of intensely fluorescent dyes and labels including HRP, biotin, ALP, Alexa Fluor® dyes, DyLight® Fluor dyes, R-phycoerythrin (R-PE), at scales from less than 100 μg up to 1 g of IgG antibody.
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Citations
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Hermanson, SB; Carlson, CB; et al. Screening for Novel LRRK2 Inhibitors Using a High-Throughput TR-FRET Cellular Assay for LRRK2 Ser935 Phosphorylation. PLOS ONE 7:-(2012).
Davies, P; Hinkle, KM; et al. Comprehensive characterization and optimization of anti-LRRK2 (leucine-rich repeat kinase 2) monoclonal antibodies. BIOCHEMICAL JOURNAL 453:101-113(2013).