Specifications
Species Reactivity
Bovine
Immunogen
Native superoxide dismutase from bovine erythrocytes
Applications
Application Notes
ELISA: 1/500 - 1/4,000;
Target
Alternative Names
SOD1; SOD1L1; superoxide dismutase [Cu-Zn]; Cu-Zn superoxide dismutase;
Product Background
Pathway
Amyotrophic lateral sclerosis (ALS); Cellular responses to stress; Detoxification of Reactive Oxygen Species; Hemostasis; Huntingtons disease; Peroxisome; Platelet activation, signaling and aggregation; Platelet degranulation;
Custom Antibody Labeling
We offer labeled antibodies using our catalogue antibody products and a broad range of intensely fluorescent dyes and labels including HRP, biotin, ALP, Alexa Fluor® dyes, DyLight® Fluor dyes, R-phycoerythrin (R-PE), at scales from less than 100 μg up to 1 g of IgG antibody.
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Citations
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Redler, RL; Fee, L; et al. Non-native Soluble Oligomers of Cu/Zn Superoxide Dismutase (SOD1) Contain a Conformational Epitope Linked to Cytotoxicity in Amyotrophic Lateral Sclerosis (ALS). BIOCHEMISTRY 53:2423-2432(2014).
Bros-Facer, V; Krull, D; et al. Treatment with an antibody directed against Nogo-A delays disease progression in the SOD1(G93A) mouse model of Amyotrophic lateral sclerosis. HUMAN MOLECULAR GENETICS 23:4187-4200(2014).