Anti-SOD1 polyclonal antibody [FITC]
Rabbit Anti-Human SOD1 (full length) polyclonal antibody for WB, IP, IHC-P, IHC-Fr
COA
Specifications
Antibody Isotype
IgG
Species Reactivity
Mouse, Rat, Sheep, Rabbit, Hamster, Cow, Dog, Human, Pig, Monkey
Immunogen
Full length protein corresponding to Human Superoxide Dismutase 1 aa 1-154. (NP_000445.1).Sequence: MATKAVCVLKGDGPVQGIINFEQKESNGPVKVWGSIKGLTEGLHGFHVHE FGDNTAGCTSAGPHFNPLSRKHGGPKDEERHVGDLGNVTADKDGVADVSI EDSVISLSGDHCIIGRTLVV HEKADDLGKGGNEESTKTGNAGSRLACG VIG
Conjugate
FITC
Applications
Application Notes
WB: 0.2 μg/ml;
Target
Alternative Names
SOD1; superoxide dismutase 1, soluble; ALS; SOD; ALS1; IPOA; hSod1; HEL-S-44; homodimer; superoxide dismutase [Cu-Zn]; SOD, soluble; indophenoloxidase A; Cu/Zn superoxide dismutase; superoxide dismutase, cystolic; epididymis secretory protein Li 44;
Entrez Gene ID
UniProt ID
Product Background
Antigen Description
Destroys radicals which are normally produced within the cells and which are toxic to biological systems.
Pathway
AGE/RAGE pathway; Amyotrophic lateral sclerosis (ALS); Cellular responses to stress; Dopamine metabolism
Citations
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Brown, HH; Borchelt, DR; et al. Analysis of Mutant SOD1 Electrophoretic Mobility by Blue Native Gel Electrophoresis; Evidence for Soluble Multimeric Assemblies. PLOS ONE 9:-(2014).
Rotunno, MS; Auclair, JR; et al. Identification of a Misfolded Region in Superoxide Dismutase 1 That Is Exposed in Amyotrophic Lateral Sclerosis. JOURNAL OF BIOLOGICAL CHEMISTRY 289:28527-28538(2014).
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Catalog # DPABH-14356
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