Product Overview
Blocking/Immunizing peptide for anti-SOD1 antibody
Tag/Conjugate
Unconjugated
Application Notes
For in vitro research use only. Not intended for any diagnostic or therapeutic purpose. Not for human or animal consumption.
Format
Lyophilized powder
Storage
Shipped at ambient temperature, store at -20°C.
Antigen Description
The protein encoded by this gene binds copper and zinc ions and is one of two isozymes responsible for destroying free superoxide radicals in the body. The encoded isozyme is a soluble cytoplasmic protein, acting as a homodimer to convert naturally-occuring but harmful superoxide radicals to molecular oxygen and hydrogen peroxide. The other isozyme is a mitochondrial protein. Mutations in this gene have been implicated as causes of familial amyotrophic lateral sclerosis. Rare transcript variants have been reported for this gene. [provided by RefSeq, Jul 2008]
Function
chaperone binding; copper ion binding; metal ion binding; oxidoreductase activity; protein binding; protein homodimerization activity; protein phosphatase 2B binding; superoxide dismutase activity; zinc ion binding;
Synonyms
SOD1; superoxide dismutase 1, soluble; ALS, ALS1, amyotrophic lateral sclerosis 1 (adult); superoxide dismutase [Cu-Zn]; IPOA; SOD, soluble; indophenoloxidase A; Cu/Zn superoxide dismutase; superoxide dismutase, cystolic; ALS; SOD; ALS1; hSod1; homodimer;
Citations
Have you cited CDBP2768 in a publication?
Let us know and earn a reward for your research.
Product Name |
Cat. No. |
Applications |
Host Species |
Datasheet |
Price |
Add to Basket |
Product Name |
Cat. No. |
Applications |
Host Species |
Datasheet |
Price |
Add to Basket |
Brown, HH; Borchelt, DR; et al. Analysis of Mutant SOD1 Electrophoretic Mobility by Blue Native Gel Electrophoresis; Evidence for Soluble Multimeric Assemblies. PLOS ONE 9:-(2014).
Bros-Facer, V; Krull, D; et al. Treatment with an antibody directed against Nogo-A delays disease progression in the SOD1(G93A) mouse model of Amyotrophic lateral sclerosis. HUMAN MOLECULAR GENETICS 23:4187-4200(2014).