Tag/Conjugate
Unconjugated
Storage
Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles. Information available upon request.
Antigen Description
The protein encoded by this gene binds copper and zinc ions and is one of two isozymes responsible for destroying free superoxide radicals in the body. The encoded isozyme is a soluble cytoplasmic protein, acting as a homodimer to convert naturally-occuring but harmful superoxide radicals to molecular oxygen and hydrogen peroxide. The other isozyme is a mitochondrial protein. Mutations in this gene have been implicated as causes of familial amyotrophic lateral sclerosis. Rare transcript variants have been reported for this gene. [provided by RefSeq, Jul 2008]
Function
Rac GTPase binding; chaperone binding; copper ion binding; identical protein binding; protein binding; protein homodimerization activity; protein phosphatase 2B binding; superoxide dismutase activity; superoxide dismutase activity; superoxide dismutase ac
Synonyms
SOD1; superoxide dismutase 1, soluble; ALS; SOD; ALS1; IPOA; hSod1; HEL-S-44; homodimer; superoxide dismutase [Cu-Zn]; SOD, soluble; indophenoloxidase A; Cu/Zn superoxide dismutase; superoxide dismutase, cystolic; epididymis secretory protein Li 44;
Citations
Have you cited DAG-P1196 in a publication?
Let us know and earn a reward for your research.
Product Name |
Cat. No. |
Applications |
Host Species |
Datasheet |
Price |
Add to Basket |
Product Name |
Cat. No. |
Applications |
Host Species |
Datasheet |
Price |
Add to Basket |
Rotunno, MS; Auclair, JR; et al. Identification of a Misfolded Region in Superoxide Dismutase 1 That Is Exposed in Amyotrophic Lateral Sclerosis. JOURNAL OF BIOLOGICAL CHEMISTRY 289:28527-28538(2014).
Tajiri, N; Quach, DM; et al. Behavioral and Histopathological Assessment of Adult Ischemic Rat Brains after Intracerebral Transplantation of NSI-566RSC Cell Lines. PLOS ONE 9:-(2014).