Product Overview
A DNA sequence encoding human neuropilin-1 (a.a 22-644) was expressed with a polyhistidine tag and an Avi tag at the C-terminus.
Molecular Weight
73.5 kDa
Purity
> 95 % as determined by SDS-PAGE
Buffer
Lyophilized from 0.22 μm filtered solution in PBS, pH7.4
Storage
Store at -20°C to -80°C
Introduction
Neuropilin-1 is a protein that in humans is encoded by the NRP1 gene. In humans, the neuropilin 1 gene is located at 10p11.22. This is one of two human neuropilins.
Keywords
Neuropilin-1; NRP1
Citations
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Liang, WC; Dennis, MS; et al. Function blocking antibodies to neuropilin-1 generated from a designed human synthetic antibody phage library. JOURNAL OF MOLECULAR BIOLOGY 366:815-829(2007).
Weekes, C; Hedge, P; et al. A phase I dose-escalation study of the fully human monoclonal antibody MNRP1685A (anti-NRP1) administered intravenously to patients with advanced solid tumors. EJC SUPPLEMENTS 8:118-118(2010).