SARS Spike protein (aa 1 - 1190) [His]

Product Overview

6xHis tagged Spike protein (amino acid 1-1190) (SARS-CoV) (Beijing02) (Genebank No.AY278487)

Nature

Recombinant

Tag/Conjugate

His

Molecular Weight

comprises 665 amino acids and has a predicted molecular mass of 142.8 kDa. As a result of high glycosylation, the apparent molecular mass of the protein is approximately 190-200 kDa in SDS-PAGE under reducing conditions

Purity

≥ 95%

Format

Liquid

Concentration

1 mg/mL

Buffer

PBS containing 0.1% BSA and 25% glycerol.

Preservative

None

Storage

Store at 4°C; DO NOT FREEZE; stable for 1 year from the date of shipment.

Stability

Samples are stable for up to twelve months from date of receipt at -70 ℃

Introduction

SARS Coronavirus is an enveloped virus containing three outer structural proteins, namely the membrane (M), envelope (E), and spike (S) proteins. Spike (S)-glycoprotein of the virus interacts with a cellular receptor and mediates membrane fusion to allow viral entry into susceptible target cells. Accordingly, S-protein plays an important role in virus infection cycle and is the primary target of neutralizing antibodies. The E.Coli derived 38 kDa mosaic protein contains the N-terminal section of the Spike protein.