COA
Target
ZnT8
Nature
Recombinant
Tag/Conjugate
His
Purity
> 90% as determined by SDS-PAGE
Format
Liquid
Buffer
20 mM Tris-HCl, pH 8.0, 50% glycerol
Preservative
None
Storage
Store at -20°C
Introduction
Zinc transporter 8 (ZNT8) is a protein that in humans is encoded by the SLC30A8 gene. ZNT8 is a zinc transporter related to insulin secretion in humans. Certain alleles of the SLC30A8 gene may increase the risk for developing type 2 diabetes, but a loss-of-function mutation appears to greatly reduce the risk of diabetes.
Keywords
Zinc transporter 8; ZNT8
Citations
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Andersen, MK; Harkonen, T; et al. Zinc transporter type 8 autoantibodies (ZnT8A): prevalence and phenotypic associations in latent autoimmune diabetes patients and patients with adult onset type 1 diabetes. AUTOIMMUNITY 46:251-258(2013).
Kawasaki, E; et al. ZnT8 and type 1 diabetes. ENDOCRINE JOURNAL 59:531-537(2012).
![Recombinant Human Zinc transporter 8 [His] (DAGC025)](png/dagc025-1.png)
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Catalog # DAG-WT1343
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