Magic™ Anti-alpha Synuclein monoclonal antibody
Mouse Anti-Human alpha Synuclein (Phospho S129) monoclonal antibody for IHC-P
COA
Specifications
Antibody Isotype
IgG2a
Clone
Q-tzo/92B
Species Reactivity
Human
Immunogen
Synthetic peptide corresponding to Human alpha Synuclein aa 124-134 (phospho S129) conjugated to Keyhole Limpet Haemocyanin (KLH) (Cysteine residue).Sequence: AYEMPSEEGYQ Database link: P37840
Conjugate
Unconjugated
Applications
Application Notes
IHC-P: 1/500 - 1/1000.
Target
Alternative Names
SNCA; synuclein, alpha (non A4 component of amyloid precursor); PARK1, PARK4, Parkinson disease (autosomal dominant, Lewy body) 4; alpha-synuclein; alpha synuclein; NACP; PD1; synuclein alpha-140; non A-beta component of AD amyloid; PARK1; PARK4; MGC1109
Entrez Gene ID
UniProt ID
Product Background
Antigen Description
May be involved in the regulation of dopamine release and transport. Induces fibrillization of microtubule-associated protein tau. Reduces neuronal responsiveness to various apoptotic stimuli, leading to a decreased caspase-3 activation.
Pathway
Alpha-synuclein signaling, organism-specific biosystem; Alzheimers disease, organism-specific biosystem; Alzheimers disease, conserved biosystem; Amyloids, organism-specific biosystem; Disease, organism-specific biosystem; EGFR1 Signaling Pathway, organism-specific biosystem; Parkinsons disease, organism-specific biosystem;
Custom Antibody Labeling
We offer labeled antibodies using our catalogue antibody products and a broad range of intensely fluorescent dyes and labels including HRP, biotin, ALP, Alexa Fluor® dyes, DyLight® Fluor dyes, R-phycoerythrin (R-PE), at scales from less than 100 μg up to 1 g of IgG antibody. Learn More
Citations
Have you cited DCABH-7907 in a publication? Let us know and earn a reward for your research.
| Product Name | Cat. No. | Applications | Host Species | Datasheet | Price | Add to Basket |
|---|
Ling, H; Kara, E; et al. TDP-43 pathology in a patient carrying G2019S LRRK2 mutation and a novel p.Q124E MAPT. NEUROBIOLOGY OF AGING 34:-(2013).
Bennett, DA; Schneider, JA; et al. Mild cognitive impairment is related to Alzheimer disease pathology and cerebral infarctions. NEUROLOGY 64:834-841(2005).
Online Inquiry
Catalog # DCABH-7907
Related Products
By targets
Related Resources
Ordering Information
Payment methods we support:
Invoice / Purchase Order
Credit card
Invoice / Purchase Order
Credit card
