Magic™ Anti-alpha Synuclein monoclonal antibody
Rabbit Anti-Human alpha Synuclein (Phospho S129) monoclonal antibody for WB
COA
Specifications
Antibody Isotype
IgG
Clone
NKG-S24 (9-9)
Species Reactivity
Human
Immunogen
Synthetic phosphopeptide, corresponding to residues surrounding Serine 129 of Human alpha Synuclein (UniProt: P37840).
Conjugate
Unconjugated
Applications
Application Notes
WB: 1/1000
Target
Alternative Names
SNCA; synuclein, alpha (non A4 component of amyloid precursor); PARK1, PARK4, Parkinson disease (autosomal dominant, Lewy body) 4; alpha-synuclein; alpha synuclein; NACP; PD1; synuclein alpha-140; non A-beta component of AD amyloid; PARK1; PARK4; MGC1109
Entrez Gene ID
UniProt ID
Product Background
Antigen Description
May be involved in the regulation of dopamine release and transport. Induces fibrillization of microtubule-associated protein tau. Reduces neuronal responsiveness to various apoptotic stimuli, leading to a decreased caspase-3 activation.
Pathway
Alpha-synuclein signaling, organism-specific biosystem; Alzheimers disease, organism-specific biosystem; Alzheimers disease, conserved biosystem; Amyloids, organism-specific biosystem; Disease, organism-specific biosystem; EGFR1 Signaling Pathway, organism-specific biosystem; Parkinsons disease, organism-specific biosystem;
Custom Antibody Labeling
We offer labeled antibodies using our catalogue antibody products and a broad range of intensely fluorescent dyes and labels including HRP, biotin, ALP, Alexa Fluor® dyes, DyLight® Fluor dyes, R-phycoerythrin (R-PE), at scales from less than 100 μg up to 1 g of IgG antibody. Learn More
Citations
Have you cited DCABH-5202 in a publication? Let us know and earn a reward for your research.
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Vivacqua, G; Biagioni, F; et al. Loss of spinal motor neurons and alteration of alpha-synuclein immunostaining in MPTP induced Parkinsonism in mice. JOURNAL OF CHEMICAL NEUROANATOMY 44:76-85(2012).
Nemes, Z; Devreese, B; et al. Cross-linking of ubiquitin, HSP27, parkin and alpha-synuclein by gamma-glutamyl-epsilon-lysine bonds in Alzheimer's neurofibrillary tangles. FASEB JOURNAL 18:1135-+(2004).
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Catalog # DCABH-5202
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