Anti-CDK5 polyclonal antibody
Rabbit Anti-Human CDK5 polyclonal antibody for WB, IP, ELISA, IHC-P, ICC/IF
COA
Specifications
Antibody Isotype
IgG
Species Reactivity
Human
Immunogen
Synthetic peptide conjugated to KLH, corresponding to the C-terminus of Human Cdk5 (NP_004926.1).
Conjugate
Unconjugated
Applications
Application Notes
IHC-P: 1/500.
Target
Alternative Names
CDK5; cyclin-dependent kinase 5; PSSALRE; TPKII catalytic subunit; protein kinase CDK5 splicing; cell division protein kinase 5; serine/threonine-protein kinase PSSALRE; tau protein kinase II catalytic subunit;
Entrez Gene ID
UniProt ID
Product Background
Antigen Description
Probably involved in the control of the cell cycle. Interacts with D1 and D3-type G1 cyclins. Can phosphorylate histone H1, tau, MAP2 and NF-H and NF-M. Also interacts with p35 which activates the kinase.
Pathway
Alzheimers disease; Axon guidance; CRMPs in Sema3A signaling; Cocaine addiction;
Custom Antibody Labeling
We offer labeled antibodies using our catalogue antibody products and a broad range of intensely fluorescent dyes and labels including HRP, biotin, ALP, Alexa Fluor® dyes, DyLight® Fluor dyes, R-phycoerythrin (R-PE), at scales from less than 100 μg up to 1 g of IgG antibody. Learn More
Citations
Have you cited DPABH-12194 in a publication? Let us know and earn a reward for your research.
| Product Name | Cat. No. | Applications | Host Species | Datasheet | Price | Add to Basket |
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Van den Haute, C; Spittaels, K; et al. Coexpression of human cdk5 and its activator p35 with human protein tau in neurons in brain of triple transgenic mice. NEUROBIOLOGY OF DISEASE 8:32-44(2001).
Hahn, CM; Kleinholz, H; et al. Role of cyclin-dependent kinase 5 and its activator P35 in local axon and growth cone stabilization. NEUROSCIENCE 134:449-465(2005).
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Catalog # DPABH-12194
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