Anti-CDK5 polyclonal antibody
Rabbit Anti-Human CDK5 (aa 229-292) polyclonal antibody for WB, IHC-P, ICC/IF
COA
Specifications
Antibody Isotype
IgG
Species Reactivity
Mouse, Human
Immunogen
Synthetic peptide, corresponding to a region within C terminal amino acids 229-292 of Human Cdk5.
Conjugate
Unconjugated
Applications
Application Notes
WB: 1/500 - 1/3000; IHC-P: 1/100 - 1/1000; ICC/IF: 1/100 - 1/1000.
Target
Alternative Names
CDK5; cyclin-dependent kinase 5; PSSALRE; TPKII catalytic subunit; protein kinase CDK5 splicing; cell division protein kinase 5; serine/threonine-protein kinase PSSALRE; tau protein kinase II catalytic subunit;
Entrez Gene ID
UniProt ID
Product Background
Antigen Description
Probably involved in the control of the cell cycle. Interacts with D1 and D3-type G1 cyclins. Can phosphorylate histone H1, tau, MAP2 and NF-H and NF-M. Also interacts with p35 which activates the kinase.
Pathway
Alzheimers disease; Axon guidance; CRMPs in Sema3A signaling; Cocaine addiction;
Custom Antibody Labeling
We offer labeled antibodies using our catalogue antibody products and a broad range of intensely fluorescent dyes and labels including HRP, biotin, ALP, Alexa Fluor® dyes, DyLight® Fluor dyes, R-phycoerythrin (R-PE), at scales from less than 100 μg up to 1 g of IgG antibody. Learn More
Citations
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| Product Name | Cat. No. | Applications | Host Species | Datasheet | Price | Add to Basket |
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Augustinack, JC; Sanders, JL; et al. Colocalization and fluorescence resonance energy transfer between cdk5 and AT8 suggests a close association in pre-neurofibrillary tangles and neurofibrillary tangles. JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY 61:557-564(2002).
Bertelli, E; Regoli, M; et al. Nestin expression in adult and developing human kidney. JOURNAL OF HISTOCHEMISTRY & CYTOCHEMISTRY 55:411-421(2007).
Online Inquiry
Catalog # DPABH-03356
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