Magic™ Anti-alpha Synuclein monoclonal antibody
Rabbit Anti-Human alpha Synuclein (Phospho S129) monoclonal antibody for WB, ICC/IF
COA
Specifications
Antibody Isotype
IgG
Clone
FQ2647Z
Species Reactivity
Mouse, Rat, Human
Immunogen
A phosphor-specific peptide corresponding to residues surrounding Serine 129 of human alpha Synuclein.
Conjugate
Unconjugated
Applications
Application Notes
WB: 1/5000
Target
Alternative Names
SNCA; synuclein, alpha (non A4 component of amyloid precursor); PARK1, PARK4, Parkinson disease (autosomal dominant, Lewy body) 4; alpha-synuclein; alpha synuclein; NACP; PD1; synuclein alpha-140; non A-beta component of AD amyloid; PARK1; PARK4; MGC1109
Entrez Gene ID
UniProt ID
Product Background
Antigen Description
May be involved in the regulation of dopamine release and transport. Induces fibrillization of microtubule-associated protein tau. Reduces neuronal responsiveness to various apoptotic stimuli, leading to a decreased caspase-3 activation.
Pathway
Alpha-synuclein signaling, organism-specific biosystem; Alzheimers disease, organism-specific biosystem; Alzheimers disease, conserved biosystem; Amyloids, organism-specific biosystem; Disease, organism-specific biosystem; EGFR1 Signaling Pathway, organism-specific biosystem; Parkinsons disease, organism-specific biosystem;
Custom Antibody Labeling
We offer labeled antibodies using our catalogue antibody products and a broad range of intensely fluorescent dyes and labels including HRP, biotin, ALP, Alexa Fluor® dyes, DyLight® Fluor dyes, R-phycoerythrin (R-PE), at scales from less than 100 μg up to 1 g of IgG antibody. Learn More
Citations
Have you cited DCABH-9034 in a publication? Let us know and earn a reward for your research.
| Product Name | Cat. No. | Applications | Host Species | Datasheet | Price | Add to Basket |
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Ito, K; Arai, K; et al. Astrocytic tau pathology positively correlates with neurofibrillary tangle density in progressive supranuclear palsy. ACTA NEUROPATHOLOGICA 115:623-628(2008).
Tanikawa, S; Mori, F; et al. Endosomal sorting related protein CHMP2B is localized in Lewy bodies and glial cytoplasmic inclusions in alpha-synucleinopathy. NEUROSCIENCE LETTERS 527:16-21(2012).
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Catalog # DCABH-9034
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