Magic™ Anti-alpha Synuclein polyclonal antibody
Rabbit Anti-Human alpha Synuclein (Phospho Y136) polyclonal antibody for WB, ICC/IF
COA
Specifications
Antibody Isotype
IgG
Species Reactivity
Mouse, Rat, Human
Immunogen
Synthetic peptide conjugated to KLH, surrounding phosphorylation site of Tyrosine 136 (Q-D-Y(p)-E-P) derived from Human alpha synuclein (NP_000336.1)
Conjugate
Unconjugated
Applications
Application Notes
WB: 1/500 - 1/1000; ICC/IF: 1/100 - 1/200.
Target
Alternative Names
SNCA; synuclein, alpha (non A4 component of amyloid precursor); PD1; NACP; PARK1; PARK4; alpha-synuclein; synuclein alpha-140; non A-beta component of AD amyloid;
Entrez Gene ID
UniProt ID
Product Background
Antigen Description
May be involved in the regulation of dopamine release and transport. Induces fibrillization of microtubule-associated protein tau. Reduces neuronal responsiveness to various apoptotic stimuli, leading to a decreased caspase-3 activation.
Pathway
Alpha-synuclein signaling; Alzheimers disease; Amyloids; EGFR1 Signaling Pathway
Custom Antibody Labeling
We offer labeled antibodies using our catalogue antibody products and a broad range of intensely fluorescent dyes and labels including HRP, biotin, ALP, Alexa Fluor® dyes, DyLight® Fluor dyes, R-phycoerythrin (R-PE), at scales from less than 100 μg up to 1 g of IgG antibody. Learn More
Citations
Have you cited DPABH-25130 in a publication? Let us know and earn a reward for your research.
| Product Name | Cat. No. | Applications | Host Species | Datasheet | Price | Add to Basket |
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Sato, K; Kaji, R; et al. Compartmental loss of striatal medium spiny neurons in multiple system atrophy of parkinsonian type. MOVEMENT DISORDERS 22:2365-2370(2007).
Vivacqua, G; Biagioni, F; et al. Loss of spinal motor neurons and alteration of alpha-synuclein immunostaining in MPTP induced Parkinsonism in mice. JOURNAL OF CHEMICAL NEUROANATOMY 44:76-85(2012).
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Catalog # DPABH-25130
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